IN VITRO ANTILEUKEMIC ACTIVITY OF EUPHORBIA ECHINUS EXTRACT

Aim. Cancer continues to pose a serious threat human health. Euphorbia plants are rich in phenolics, aromatic esters, steroids and several bioactive compounds. Studies have shown the presence of large number compounds E. echinus including flavonoids, proanthocyanins. Method. There it was investigated cytotoxic effects methanolic extract on K562, HL60, Ishikawa, Raji SH-SY5Y cells. Results. The found be highly against HL60 K562 (79.78 76.44% cytotoxicity, respectively). DNA fragmentation exclusively observed cells indicating that reduction viable following treatment with is due apoptosis. Conclusions. Our results suggest might drug potential leukemic